羊搔痒症(英语:Scrapie),是一种退化性疾病,发生在绵羊及山羊上[1],造成它们的神经系统异常。它跟牛海绵状脑病与鹿的慢性消耗病相同,都是传染性海绵状脑病的一种,由异常的朊毒体蛋白所引起[2]。它在1732年于英国的牧场发现。目前没有传染至人体的病例[3][4]。
瘙痒通常影响3至5岁左右的羊。羊出生时和与胎盘组织接触的传播潜力是显而易见的。没有证据显示羊搔痒症能传染给人类[5]。
羊搔痒症的名称来自于它在诊断上特别的病征,受到感染的羊,会不停的摩擦石头、树或篱笆来抓痒[6]。
参阅
参考资料
- ↑ Detwiler LA. Scrapie. Rev. - Off. Int. Epizoot. 1992, 11 (2): 491–537. PMID 1617202.
- ↑ Hunter N. Scrapie: uncertainties, biology and molecular approaches. Biochim. Biophys. Acta. 2007, 1772 (6): 619–28. PMID 17560089. doi:10.1016/j.bbadis.2007.04.007.
- ↑ National Scrapie Education Initiative. Scrapie Fact Sheet. National Institute for Animal Agriculture. [4 December 2011].
- ↑ Rolf, George. From Sheep to Humans: Scrapie and Creutzfeldt–Jakob Disease. Ecclectica. [4 December 2011].
- ↑ Scrapie reviewed and published by WikiVet, accessed 12 October 2011.
- ↑ Foster JD, Parnham D, Chong A, Goldmann W, Hunter N. Clinical signs, histopathology and genetics of experimental transmission of BSE and natural scrapie to sheep and goats. Vet. Rec. 2001, 148 (6): 165–71. PMID 11258721. doi:10.1136/vr.148.6.165.